Head and Neck Cancer
Conditions
Keywords
Head and neck cancer, Radiotherapy, Dysphagia, Exercise, Deglutition, Randomized controlled trial, Quality of life, Tube feeding
Brief summary
Background: Dysphagia is a common side effect after radiotherapy for haed and neck cancer patients. It may be worsened by immobility of the throat during tube feeding. Hypothesis: Exercises may prevent or reduce late dysphagia. Method: Phase I study to identify the tolerated intensity of exercises and establish the method of measuring training intensity and dysphagia measurement. Endpoint: Objective dysphagia using VF and FEESST. The HN swallowing and HN pain endpoint of EORTC H&N35 questionnaire. Weight loss, duration of tube feeding.
Interventions
BEHAVIORALSwallowing Exercises
Daily exercises
Sponsors
University of Aarhus
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Head and neck cancer * Planned curative radiotherapy * Planned irradiation of level II+III lymph nodes \>46 Gy * \>=18 y * Speaks and reads Danish * No previous Surgery to the head and neck area except biopsies
Exclusion criteria
\-
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Objective swallowing using videofluoroscopy and endoscopic evaluation of swallowing | 2 mths |
Secondary
| Measure | Time frame |
|---|---|
| Weight | 2 mths |
| Duration of tube feeding | 2 mths |
| Swallowing scale of EORTC HN 35 | 2 mths |
Countries
Denmark
Outcome results
None listed