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Laparoscopic Roux-en-Y Gastric Bypass Versus Laparoscopic Biliopancreatic Diversion (BPD)- Duodenal Switch for Superobesity

Laparoscopic Roux-en-Y Gastric Bypass vs. Laparoscopic BPD-Duodenal Switch for Superobesity (BMI > 50 kg/m2)- A Randomized Clinical Trial

Status
UNKNOWN
Phases
Phase 4
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT00327912
Acronym
ASGARD
Enrollment
60
Registered
2006-05-19
Start date
2006-04-30
Completion date
2017-12-31
Last updated
2017-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obesity, Diabetes, Hypertension

Keywords

Obesity, Surgery, Gastric bypass, Biliopancreatic diversion with Duodenal switch, Laparoscopy

Brief summary

The purpose of this study is to compare the outcome in a broad perspective after laparoscopic Roux-en-Y gastric bypass and laparoscopic BPD-duodenal switch in the treatment of superobesity (body mass index \[BMI\] \> 50 kg/m2).

Detailed description

Surgery is the only treatment of morbid obesity that has proven to result in efficient and long lasting weight loss. There are few studies comparing different surgical techniques, especially in a randomized setting. Superobesity (BMI \> 50 kg/m2) demands an efficient surgical approach to result in satisfying weight loss. Laparoscopic techniques have been established to perform Roux-en-Y Gastric bypass and Biliopancreatic Diversion with Duodenal Switch which both are good options for treating superobesity. This study aims to compare the outcome after surgery in a broad perspective (weight loss, metabolic normalization, gastro-intestinal side effects, eating patterns, body composition, health economics). Patients will be randomized to either surgical procedure and will be followed for five years.

Interventions

PROCEDURELaparoscopic Biliopancreatic diversion with Duodenal switch

Sponsors

Helse Sor-Ost
CollaboratorOTHER_GOV
Göteborg University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
20 Years to 50 Years
Healthy volunteers
No

Inclusion criteria

* BMI 50-60 kg/m2

Exclusion criteria

* Prior obesity operation * Prior major abdominal surgical procedure * Severe disabling cardiopulmonary disease * Malignancy * Oral steroid treatment * Condition associated with poor compliance

Design outcomes

Primary

MeasureTime frame
BMI5 y
Metabolic normalization5y
Gastro-intestinal side effects5y

Secondary

MeasureTime frame
Quality of life5y
Health economics5y
Eating pattern5y
Vitamin/mineral deficiencies5y
Body composition5y

Countries

Norway, Sweden

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Apr 3, 2026