Shoulder Dislocation
Conditions
Keywords
Sedation, Propofol, Remifentanil, recovery
Brief summary
For reduction of dislocated shoulder, sedation with propofol and remifentanil should give satisfactory operating conditions and pain relief, and significantly reduce the time to full recovery, compared with morphine and midazolam
Detailed description
Propofol is a recognised agent for sedation and remifentanil is a short acting opioid analgesic. We intend to provide sedation with propofol, 0.5 mg/Kg, and analgesia with remifentanil 0.5 microgram/Kg for reduction of dislocated shoulders. This will be a randomised sex-stratified comparison with current therapy which is midazolam incrementally up to a maximum of 0.15 mg/Kg, and morphine incrementally up to 0.15 mg/Kg. The primary outcome measure is time to full recovery. Secondary aspects are pain or discomfort during the procedure and operating conditions.
Interventions
DRUGSedation with propofol and remifentanil
Sponsors
NHS Lothian
University of Edinburgh
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
16 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
\- Anterior dislocation of the shoulder suitable for manual reduction
Exclusion criteria
* significant other illness * body weight 25% greater than expected * fear of oxygen masks * alcohol intoxication
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time to full recovery | — |
Secondary
| Measure | Time frame |
|---|---|
| Operating conditions | — |
| Pain or discomfort | — |
Countries
United Kingdom
Outcome results
None listed