Open-angle Glaucoma
Conditions
Keywords
open-angle, glaucoma
Brief summary
The purpose of this study is to evaluate the safety, efficacy, and duration of effect of a single administration of Anecortave Acetate Depot for treatment of elevated intraocular pressure (IOP) in patients with open-angle glaucoma.
Interventions
Single injection, anterior juxtascleral depot (AJD)
Single injection, anterior juxtascleral depot (AJD)
Single injection, anterior juxtascleral depot (AJD)
Single injection, anterior juxtascleral depot (AJD)
Sponsors
Alcon Research
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients 18 years of age or older with open-angle glaucoma. * Other protocol-defined inclusion criteria may apply.
Exclusion criteria
* Patients with open-angle glaucoma with a pseudoexfoliation or pigment dispersion component. * Other protocol-defined
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mean change in intraocular pressure at 9 am from baseline | Weeks 2 and 6, Months 2, 3, 4, 5, 6, 7.5, 9, 10.5, and 12 |
Secondary
| Measure | Time frame |
|---|---|
| Time to treatment failure | At time point |
Outcome results
None listed