Alzheimer's Disease
Conditions
Keywords
Alzheimer's, AD, Mild Cognitive Impairment, Dementia, Cognitive remediation, computer-based training
Brief summary
The primary objective of this study is to evaluate the effects of computer-based training program (HiFi-AD) on the memory and cognitive abilities of individuals diagnosed with mild Alzheimer's Disease (AD).
Detailed description
The purpose of this study is to determine the extent to which computer-based cognitive remediation improves cognitive functions using standardized neuropsychological assessments relevant to AD; 2) the acceptability and feasibility of using computer-based cognitive remediation in an AD population.
Interventions
PROCEDUREComputer-based Cognitive Training
Sponsors
University of California, San Francisco
Posit Science Corporation
Study design
Allocation
NON_RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
60 Years to 90 Years
Healthy volunteers
No
Inclusion criteria
* Fluent in English. * Mini-Mental Status Examination (MMSE) score of 22 or higher. * Adequate visual capacity. * Adequate hearing capacity. * Has a caregiver with some computer experience. * Willing and able to commit to the time requirement of the entire study.
Exclusion criteria
* Clinically significant cerebrovascular disease. * Participant is planning to begin acetylcholinesterase inhibitor (AChEI) therapy. * Participants with severe tremor. * Axis 1 or 2 psychiatric disorders. * History of substance abuse. * History of head trauma.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary objective of this trial will be to assess the feasibility of using computer-based | — |
| cognitive training in an a population with early Alzheimer's Disease. | — |
Secondary
| Measure | Time frame |
|---|---|
| A standardized set of neuropsychological assessments will be conducted pre- and post- | — |
| compuer-based training. | — |
Countries
United States
Outcome results
None listed