Echocardiographic Study of the Haemodynamic Effects of Remifentanil With and Without Glycopyrrolate in Healthy Children

Status

Completed

Phases

Phase 2

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00315536

Enrollment

Registered

2006-04-18

Start date

2006-05-31

Completion date

2009-04-30

Last updated

2012-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Urological Surgery

Brief summary

Study to investigate the influence of remifentanil and glycopyrrolate on cardiac index and blood pressure in children.To differentiate between contractility and the effect of the circulating volume, some of the subjects will receive additional fluid.This will be evaluated using two transthoracic echocardiac exams within the first 30 min of anesthesia.

Interventions

DRUGAdministration of remifentanil and glycopyrrolate

2 mg, intravenius use

Study design

Allocation

RANDOMIZED

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

TRIPLE (Subject, Caregiver, Investigator)

Eligibility

Sex/Gender

ALL

Age

1 Years to 6 Years

Healthy volunteers

Yes

Inclusion criteria

* ASA I and II children * 1-6 years * urological surgery

Exclusion criteria

* Cardiac disease * Diabetes

Design outcomes

Primary

Measure	Time frame
Cardiac index	Twice in 16 minutes.
Blood pressure	Twice in 16 minutes.

Countries

Belgium

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026