Development of New Prenatal Diagnostic Tests From Maternal Blood

Status

Terminated

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00314691

Enrollment

Registered

2006-04-14

Start date

2006-04-30

Completion date

2006-09-30

Last updated

2011-07-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hereditary Diseases

Keywords

fetal DNA, prenatal diagnosis, maternal plasma, Diagnostic potential of cell-free fetal DNA circulating in maternal blood

Brief summary

After extraction of the cell-free DNA circulating in maternal plasma, we aim at developing new techniques for fetal DNA enrichment to perform fetal gender determination, and indirect diagnosis of inherited diseases like Cystic Fibrosis, Huntington Disease, Myotonic Dystrophy, B-Thalassaemia...

Interventions

GENETICBlood samples

Study design

Allocation

NON_RANDOMIZED

Intervention model

SINGLE_GROUP

Primary purpose

DIAGNOSTIC

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* Mother and father-to-be both older than 18 years old * Mother and father-to-be affiliated to social security * Mother and father-to-be have good understanding of the protocol * Pregnancy of the mother-to-be attested

Exclusion criteria

* Mother and father-to-be are younger than 18 years old * Mother and/or father-to be refusing to participate

Design outcomes

Primary

Measure	Time frame
Feasibility of fetal gender and genotype determination out of maternal blood	—

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026