A Study of a Glaucoma Therapy to Treat Open-Angle Glaucoma or Ocular Hypertension

Status

Completed

Phases

Phase 3

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00314171

Enrollment

437

Registered

2006-04-13

Start date

2005-10-31

Completion date

2007-08-31

Last updated

2016-11-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Open-angle Glaucoma, Ocular Hypertension

Keywords

open-angle glaucoma, ocular hypertension

Brief summary

The purpose of this study is to determine whether a glaucoma therapy is safe and effective in treating patients with open-angle glaucoma or ocular hypertension.

Interventions

DRUGBrinzolamide 10 mg/ml + Timolol 5 mg/ml eye drops, suspension

One drop in the study eye(s) twice daily for 12 months

DRUGDorzolamide 20 mg/ml + Timolol 5 mg/ml eye drops, solution (COSOPT)

One drop in the study eye(s) twice daily for 12 months

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* 18 years or older * Diagnosis of open-angle glaucoma or ocular hypertension * Other protocol-defined inclusion criteria may apply

Exclusion criteria

* Under 18 * Pregnant * Other protocol-defined

Design outcomes

Primary

Measure	Time frame
Mean IOP	—

Secondary

Measure	Time frame
Percent patients with IOP < 18 mmHg	—

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026