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A Study of a Glaucoma Therapy to Treat Open-Angle Glaucoma or Ocular Hypertension

Status
Completed
Phases
Phase 3
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT00314158
Enrollment
523
Registered
2006-04-13
Start date
2005-11-30
Completion date
2007-01-31
Last updated
2016-11-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Open-angle Glaucoma, Ocular Hypertension

Brief summary

The purpose of this study is to determine whether a glaucoma therapy is safe and effective in treating patients with open-angle glaucoma or ocular hypertension.

Interventions

DRUGBrinzolamide 10 mg/ml + Timolol 5 mg/ml eye drops, suspension

One drop twice daily in each study eye for six months

DRUGBrinzolamide 10 mg/ml (AZOPT) eye drops, suspension

One drop twice daily in each study eye for six months

DRUGTimolol 5 mg/ml eye drops, solution

One drop twice daily in each study eye for six months

Sponsors

Alcon Research
Lead SponsorINDUSTRY

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* 18 years of age or older * Diagnosis of open-angle glaucoma * Other protocol-defined inclusion criteria may apply

Exclusion criteria

* Under 18 * Pregnant * Other protocol-defined

Design outcomes

Primary

MeasureTime frame
Mean intra-ocular pressure (IOP)—

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026