Allergic Rhinitis, Asthma, Bronchial, Hypersensitivity, Immediate
Conditions
Keywords
Asthma, Allergic rhinitis, Atopy, Exhaled nitric oxide, Specific immunotherapy, Atopic diseases
Brief summary
The purpose of this study is to evaluate the immunomodulatory effect of treatment of allergic rhinitis symptoms with specific immunotherapy by measurement of pulmonary inflammatory markers, and among others, exhaled nitric oxide.
Interventions
BIOLOGICALSpecific immunotherapy
Sponsors
Bispebjerg Hospital
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 45 Years
Healthy volunteers
No
Inclusion criteria
* Age 18-45 years old * Skin prick test or RAS test and physical examination conclude that the patient will have a beneficial effect from specific immunotherapy
Exclusion criteria
* Other diseases except atopic disease * Pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Condensation of exhaled air | — |
| Skin prick test | — |
| Spirometry | — |
| Methacholine provocation of the pulmonary system | — |
| Exhaled nitric oxide | — |
| Immunoglobulin E (IgE) status | — |
| Sputum examination | — |
Secondary
| Measure | Time frame |
|---|---|
| Questionnaire | — |
Countries
Denmark
Contacts
Primary ContactThomas B Knudsen, Medical student
Backup ContactVibeke Backer, M.D., M.D.Sci
Outcome results
None listed