Visceral Leishmaniasis
Conditions
Keywords
visceral leishmaniasis, amphotericin B, Kala-azar
Brief summary
This study is being conducted to assess the safety and efficacy of amphotericin B deoxycholate in doses of 0.75 mg/kg or 1.0 mg/kg for 15 doses. In each arm the drug is given in the conventional way every alternate day against the daily administration regimen being tested.
Detailed description
This study is being conducted to assess the safety and efficacy of amphotericin B deoxycholate in doses of 0.75 mg/kg or 1.0 mg/kg for 15 doses. In each arm the drug is given in the conventional way every alternate day against the daily administration regimen being tested.
Interventions
DRUGAmphotericin B deoxycholate given as daily administration
Sponsors
Banaras Hindu University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
2 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* Parasitologically proved kala-azar
Exclusion criteria
* HIV positive serology
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Final cure rate at six months after the end of treatment | — |
Countries
India
Outcome results
None listed