Changes in Iron Markers Following Iron Loading in Hemodialysis Patients

Phase IV Study of Iron Indices' Kinetics in Hemodialysis Patients

Status

Completed

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00308490

Enrollment

160

Registered

2006-03-29

Start date

2005-09-30

Completion date

2007-01-31

Last updated

2007-03-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anemia in Chronic Renal Disease

Brief summary

The purpose of this study is to describe alterations of serum ferritin, transferrin saturation, soluble transferrin receptor, % hypochromic erythrocytes, % reticulocytes, reticulocyte hemoglobin content after iron loading in hemodialysis patients.

Interventions

DRUGiron sucrose

Study design

Allocation

NON_RANDOMIZED

Intervention model

SINGLE_GROUP

Primary purpose

DIAGNOSTIC

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* hemodialysis for three months minimum * stable epoetin dose for two months minimum * serum ferritin concentration \< 1000 ng/ml * transferrin saturation \< 50% * parathormone concentration \< 800 pg/ml

Exclusion criteria

* hemoglobin concentration \> 13g/dl * serum ferritin concentration \< 20 ng/ml * vitamin B12 and/or folic deficiency * other hematologic disease than anemia * cancer * hypothyroidism * infectious disease

Design outcomes

Primary

Measure	Time frame
Ferritin alterations after iron loading at six and twelve weeks from the beginning of iron loading.	—

Secondary

Measure	Time frame
All iron indices' alterations during twelve weeks from the beginning of iron loading.	—

Countries

Greece

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026