The Effect of CoQ10 Administration on Hemodialysis Patients

The Effect of CoQ10 Administration on the Oxidative and Antioxidative Markers in Hemodialysis Patients

Status

Completed

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00307996

Enrollment

Registered

2006-03-28

Start date

2004-03-31

Completion date

2004-12-31

Last updated

2006-03-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Renal Failure, Hemodialysis

Keywords

CoQ10, hemodialysis, oxidative marker, antioxidant

Brief summary

The purpose of this study is to examine whether CoQ10 administration is effective as an antioxidant in hemodialysis patients.

Detailed description

Oxidative stress has been recognized as a potential risk factor for such complications as atherosclerosis in hemodialysis patients. This study investigates whether CoQ10 administration is effective for protecting oxidative stress in hemodialysis patients. The subjects were recruited from day-time hemodialysis patients in Iwata City Hospital. 100 mg CoQ10 was administered every HD for 6 months. Several oxidative and antioxidative markers were measured in plasma at pre, 1, 3, 6 months and after washout.

Interventions

DRUGCoenzyme Q10 (drug)

Study design

Allocation

NON_RANDOMIZED

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

0 Years to 85 Years

Healthy volunteers

Inclusion criteria

* hemodialysis for at least 6 months

Exclusion criteria

* none

Design outcomes

Primary

Measure	Time frame
Oxidative protein concentration at 6 month	—
Antioxidant capacity at 6 month	—

Countries

Japan

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026