Effects of Ketamine On Precipitated Opioid Withdrawal Under General Anaesthesia

Status

Completed

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00300794

Enrollment

Registered

2006-03-09

Start date

2003-02-28

Completion date

2006-06-30

Last updated

2006-11-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Opiate Dependence

Brief summary

The purpose of this study is to determine whether low-dose ketamine infusion is effective in suppressing the symptoms of opiate withdrawal during rapid opiate antagonist induction (RAI).

Interventions

DRUGKetamine

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE

Eligibility

Sex/Gender

ALL

Age

18 Years to 35 Years

Healthy volunteers

Inclusion criteria

* Diagnosed opiate dependence according to ICD 10 and/or DSM 4; * Duration of substance abuse more than 1 year * No or minor co-morbidities; * Grade I-II according to physical status classification system of American Society of Anesthesiologists.

Exclusion criteria

* Current history of long acting opiate or poly-substance abuse; * Acute medical or surgical condition; * Pregnancy; * Breastfeeding.

Countries

Lithuania

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026