Type 2 Diabetes Mellitus
Conditions
Keywords
Type 2 diabetes mellitus, Macrovascular disease, Diastolic dysfunction, Intima media thickness, Single- photon emission computed tomography (SPECT)
Brief summary
The study aim is to establish a consecutive population of newly referred type 2 diabetes mellitus patients and among these to describe the degree of macrovascular disease by evaluating left ventricular systolic and diastolic function (echocardiography), myocardial perfusion (single-photon emission computed tomography (SPECT)), the peripheral vascular perfusion (strain gauge toe blood pressure measurements and a ultrasound scan of the a. carotis communis). Further, the degree of microvascular disease will be evaluated (glomerular filtration rate assessment, fundus photography and biotesiometry). Finally the cohort will be followed the next two years to assess the prognostic value of the above-mentioned parameters
Interventions
None listed
Sponsors
Odense University Hospital
Study design
Observational model
DEFINED_POPULATION
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
20 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Age: ≥ 20 years. * Fasting C-peptide \> 300 pmol/l.
Exclusion criteria
* Verified medical history of macrovascular disease (stroke, myocardiac infarct, coronary revascularisation or strain gauge toe blood pressure \< 30 mmHg). * Suspected short lifespan because of malignant disease or end-stage kidney disease. * Pregnancy or planned pregnancy during the study period. * Body weight \> 150 kg. * Physical or mental disability not enabling participation in the study.
Countries
Denmark
Contacts
Primary ContactMikael K. Poulsen, PhD student
Backup ContactJan E. Henriksen, MD, PhD
Outcome results
None listed