Oxygenation
Conditions
Keywords
Oxygenation
Brief summary
Measuring tissue oxygen saturation (St02) in the thenar eminence is emerging as a measurement of resuscitation. However, no study to our knowledge has evaluated the effects of an arterial line in the radial artery supplying this muscle bed on St02. This study will attempt to address the interaction between an arterial line and St02 monitoring in the thenar eminence. As most patients who require aggressive resuscitation will have an arterial line, it is important to understand what if any impact this will have on St02 in the same extremity.
Interventions
DEVICEStO2 monitoring
placement of the StO2 device/ external noninvasive
Sponsors
The University of Texas Health Science Center at San Antonio
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Standard of care placement of arterial line * 18 years of age or older
Exclusion criteria
* Pregnant females * Nursing mothers * Prisoners
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Tissue Oxygen Saturation (StO2) Measurement on the Extremity With a Radial Arterial Line | up to 15 minutes | Using near-infrared spectroscopy, the external device recorded raw StO2 values every 3.5 seconds for approximately 5 minutes prior to and immediately following the insertion of a radial arterial catheter on the ipsilateral side. The raw values were then compiled into one-minute averages. |
Countries
United States
Participant flow
Recruitment details
Subjects were recruited from inpatients at a local hospital's Intensive Care Unit (ICU)
Participants by arm
| Arm | Count |
|---|---|
| StO2 Values StO2 values pre and post arterial line placement. | 47 |
| Total | 47 |
Baseline characteristics
| Characteristic | StO2 Values |
|---|---|
| Age, Categorical <=18 years | 0 Participants |
| Age, Categorical >=65 years | 0 Participants |
| Age, Categorical Between 18 and 65 years | 47 Participants |
| Region of Enrollment United States | 47 participants |
| Sex: Female, Male Female | 19 Participants |
| Sex: Female, Male Male | 28 Participants |
Adverse events
| Event type | EG000 affected / at risk |
|---|---|
| deaths Total, all-cause mortality | — / — |
| other Total, other adverse events | 0 / 47 |
| serious Total, serious adverse events | 0 / 47 |
Outcome results
Primary
Tissue Oxygen Saturation (StO2) Measurement on the Extremity With a Radial Arterial Line
Using near-infrared spectroscopy, the external device recorded raw StO2 values every 3.5 seconds for approximately 5 minutes prior to and immediately following the insertion of a radial arterial catheter on the ipsilateral side. The raw values were then compiled into one-minute averages.
Time frame: up to 15 minutes
Population: Data from 18 subjects not used due to only partial data captured resulting from logistical issues.
| Arm | Measure | Value (MEAN) |
|---|---|---|
| StO2 Values | Tissue Oxygen Saturation (StO2) Measurement on the Extremity With a Radial Arterial Line | 0.68 StO2 percent saturation |
p-value: 0.5595% CI: [-0.8, 1.48]repeated measures model