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Effect of Sildenafil on Endothelial Function

Effect of Sildenafil on Endothelial Function

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT00297544
Enrollment
60
Registered
2006-02-28
Start date
2005-10-31
Completion date
Unknown
Last updated
2006-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Impotence

Keywords

impotence, endothelial function, autonomic nervous system

Brief summary

We are investigating the chronic effect of daily assumption of Viagra on the blood vessels function in patients with impotence. The study will include 2 groups: 1- patients with multiple risk factors, e.g. hypertension 2- patients with no cardiovascular risk factors

Detailed description

We are investigating the chronic effect of daily assumption of Viagra on the blood vessels function in patients with impotence. The study will include 2 groups: 1- patients with multiple risk factors, e.g. hypertension 2- patients with no cardiovascular risk factors

Interventions

DRUGViagra

Sponsors

Pfizer
CollaboratorINDUSTRY
Rambam Health Care Campus
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
ECT
Masking
DOUBLE

Eligibility

Sex/Gender
MALE
Age
40 Years to 70 Years
Healthy volunteers
No

Inclusion criteria

* age 40-70 * impotence * with and without hypertension, Hypercholesteremia or DM

Exclusion criteria

* CHF: NYHA \> II * Stable angina: CCS \> II * Nitrate treatment

Design outcomes

Primary

MeasureTime frame
Improvement of endothelial function following Viagra treatment, according to platismographia.—

Countries

Israel

Contacts

Primary ContactGiris Jacob, Prof., MD, DSc
g_jacob@rambam.health.gov.il972-4-854-2467
Backup ContactYuram Vardi, Prof., MD
y_vardi@rambam.health.gov.il972-4-854-2819

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026