123I-MIBG SPECT/CT for Assessment of Cardiac Sympathetic Innervation

Quantitative 123I-MIBG SPECT/CT Assessment of Cardiac Sympathetic Innervation

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00296738

Enrollment

Registered

2006-02-27

Start date

2007-05-31

Completion date

2010-05-31

Last updated

2011-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiac Diseases

Brief summary

Myocardial scintigraphy with 123I-MIBG allows for visual and semi-quantitative assessment of sympathetic cardiac innervation using the hear to mediastinum ratio (HMR). Impaired cardiac MIBG clearance may occur in patients with congestive heart failure (CHF). The purpose of present study was to develop and validate a quantitative index for the assessment of cardiac MIBG uptake kinetics using SPECT/CT for diagnosis of CHF

Interventions

DEVICESPECT/CT

GE INFINIA HAWKEYE

Study design

Observational model

CASE_ONLY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

40 Years to No maximum

Healthy volunteers

Inclusion criteria

* age\>40

Exclusion criteria

* none

Design outcomes

Primary

Measure	Time frame
The impact of the imaging modality on patient management	2 years

Secondary

Measure	Time frame
The impact on patient management	2 years

Countries

Israel

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026