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The Effect of Mild Traumatic Brain Injury on Recovery From Injury

The Effect of Mild Traumatic Brain Injury on Recovery From Injury

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT00295074
Enrollment
800
Registered
2006-02-22
Start date
2004-10-31
Completion date
2007-09-30
Last updated
2008-02-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Brain Concussion, Head Injury, Trauma, Traumatic Brain Injury

Keywords

traumatic brain injury, head injury, concussion, neuropsychologic test

Brief summary

Mild traumatic brain injury (TBI) is a common injury that can produce significant functional sequelae and ongoing disabling symptoms. Predicting who will have an uncomplicated recovery and who will suffer ongoing symptoms is difficult. This protocol evaluates the use of neuropsychologic testing after mild TBI in injured patients to attempt to objectively establish predictors of long term disability and functional recovery.

Detailed description

Patients who are hospitalized and who have suffered mild TBI (loss of consciousness or post-traumatic amnesia; Glasgow Coma Score 13-15; admitted within 24 hours of injury; able to read, speak, and understand English) who do not have pre-injury dementia or significant cognitive impairment will undergo computerized neuropsychologic testing using a previously validated tool that has been effective in sports-related mild TBI. Sequential testing will be performed during recovery and patients who report disabling symptoms and/or functional impairment will be compared to patients who recover uneventfully. Goal is to identify those parameters that predict early who may suffer long term sequelae or functional impairment and therefore benefit from early cognitive rehabilitation. Secondary goals are to establish objective parameters for functional recovery after mild TBI.

Interventions

PROCEDUREneuropsychologic testing

Sponsors

University of Pittsburgh
Lead SponsorOTHER

Study design

Allocation
NON_RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Mild TBI * Admitted within 24 hours of injury * Able to read, speak,and understand English

Exclusion criteria

* Expected to die of their injuries * Pre-existing dementia or significant cognitive impairment * Neurologically impaired and incapable of completing testing * Physically incapable of using arms/hands to complete computerized testing

Design outcomes

Primary

MeasureTime frame
functional outcome
subjective symptoms

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026