Coronary Artery Disease
Conditions
Keywords
Coronary calcium score, Coronary artery disease, Cardiac transplantation, Coronary calcium score in heart transplanted patients, Coronary artery disease in heart transplanted patients
Brief summary
The purpose of the study is to determine if calcium score can be used as a predictor of coronary artery disease in heart transplanted patients, as it is used in non-transplanted persons.
Detailed description
Several studies have shown that a negative calcium score is a strong independent negative predictor of coronary artery disease (CAD). CAD in heart transplants (HTx) differs from CAD lesions in native hearts. The aim of this study is to see if there is a similar relation between coronary artery calcium and CAD in transplanted hearts as in native hearts.
Interventions
PROCEDUREMDCT calcium score
Sponsors
Oslo University Hospital
Study design
Allocation
NON_RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Heart transplanted patient * Aged 18 or above.
Exclusion criteria
* Pregnancy * Atrial fibrillation * Severe heart failure New York Heart Association (NYHA) class IV * Severe pulmonary disease making the patient unable to hold his/her breath for more than 10 seconds.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Calcium score | at the date of examination |
Secondary
| Measure | Time frame |
|---|---|
| Coronary stenoses found on coronary angiography | at the date of examination |
Countries
Norway
Outcome results
None listed