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Use of Arimidex and Zoladex as Pretreatment to IVF in Women With Ovarian Endometriosis

Status
Completed
Phases
Phase 4
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT00286351
Enrollment
20
Registered
2006-02-03
Start date
2005-01-31
Completion date
Unknown
Last updated
2007-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Endometriosis

Brief summary

Does a combination of Arimidex and Zoladex make endometriomas shrink and how is the following IVF outcome

Interventions

DRUGCombined treatment with Arimidex and Zoladex before IVF

Sponsors

Rigshospitalet, Denmark
Lead SponsorOTHER

Study design

Allocation
NON_RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
FEMALE
Age
20 Years to 40 Years
Healthy volunteers
No

Inclusion criteria

* Endometrioma(s)with a size of 20-70 mm, persisted for at least 3 cycles * Couples with indication and wish for IVF/ICSI * Age of women: 20-40 years * Regular menstrual cycle within normal range (21-35 days) * Body Mass Index (BMI): 18-30 kg/m2

Exclusion criteria

* History with osteoporosis, liver-, kidney- or heart disease or thromboembolic disease * Treatment of endometriosis with GnRH agonist during the last 3 month

Design outcomes

Primary

MeasureTime frame
size of endometriomas after 2½ month of combined downregulation

Countries

Denmark

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026