Endometriosis
Conditions
Brief summary
Does a combination of Arimidex and Zoladex make endometriomas shrink and how is the following IVF outcome
Interventions
DRUGCombined treatment with Arimidex and Zoladex before IVF
Sponsors
Rigshospitalet, Denmark
Study design
Allocation
NON_RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
20 Years to 40 Years
Healthy volunteers
No
Inclusion criteria
* Endometrioma(s)with a size of 20-70 mm, persisted for at least 3 cycles * Couples with indication and wish for IVF/ICSI * Age of women: 20-40 years * Regular menstrual cycle within normal range (21-35 days) * Body Mass Index (BMI): 18-30 kg/m2
Exclusion criteria
* History with osteoporosis, liver-, kidney- or heart disease or thromboembolic disease * Treatment of endometriosis with GnRH agonist during the last 3 month
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| size of endometriomas after 2½ month of combined downregulation | — |
Countries
Denmark
Outcome results
None listed