Dosage of Metal Ions in the Blood of Different Metal-on-metal Prostheses, in Correlation With Physical Activity

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00285974

Enrollment

120

Registered

2006-02-02

Start date

2003-12-31

Completion date

2005-11-30

Last updated

2022-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hip Osteoarthritis

Brief summary

Prospective study including 6 groups of 20 patients with a total hip prosthesis. Five different types of metal-on-metal prostheses are studied, and 1 group with ceramic-on-ceramic prostheses acts as control group. Patients undergo a clinical evaluation and blood sampling preoperatively, and 3, 6, 12 and 24 months postoperatively.

Interventions

DEVICEmetal-on-metal total hip prosthesis versus ceramic-on-ceramic total hip prosthesis

metal-on-metal total hip prosthesis versus ceramic-on-ceramic total hip prosthesis

Study design

Allocation

NON_RANDOMIZED

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

25 Years to 65 Years

Healthy volunteers

Inclusion criteria

* Hip osteoarthritis

Exclusion criteria

Design outcomes

Primary

Measure	Time frame
Concentration of metal ions in the blood	preoperatively, and 3, 6, 12 and 24 months postoperatively.

Countries

Belgium

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026