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Early Exposure to Lead and Adult Antisocial Outcomes

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT00285610
Enrollment
225
Registered
2006-02-02
Start date
2001-11-30
Completion date
2006-10-31
Last updated
2014-11-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lead Poisoning

Brief summary

Prior research indicates a link between early lead exposure and risk for delinquent behavior. In this study, we follow a large birth cohort from the Cincinnati Lead Study into early adulthood to determine whether this increased risk persists. Outcome measures include official arrest records, diagnoses of Substance Abuse Disorder and Antisocial Personality Disorder, self-report of delinquent behavior, and a psychopathy scale. Predictors include pre-natal and post-natal blood lead levels. Multivariate statistical methods will control for potential confounders/covariates.

Interventions

None listed

Sponsors

National Institute of Environmental Health Sciences (NIEHS)
Lead SponsorNIH

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

(1) Part of original CLS birth cohort -

Exclusion criteria

(1) Moved out of geographic area \-

Design outcomes

Primary

MeasureTime frame
Lead Exposure and Antisocial BehaviorPrenatal (1-2 trimester) and postnatal on a quarterly and bi-annual basis (until 6.5 years)

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026