PEEP Test and Gas Exchange in ALI/ARDS Patients

Positive End Expiratory Pressure (PEEP) Test and Gas Exchange in ALI/ARDS Patients

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00284102

Enrollment

Registered

2006-01-31

Start date

2006-01-31

Completion date

2008-04-30

Last updated

2008-09-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Respiratory Distress Syndrome

Keywords

gas exchange, dead space, respiratory failure, ALI/ARDS patients

Brief summary

The investigators aim to study the effect of different levels of PEEP in ALI/ARDS patients on gas exchange.

Detailed description

In a population of ALI/ARDS patients during mechanical ventilation we will evaluate the effect of different levels of PEEP on gas exchange and dead space.

Interventions

PROCEDUREMechanical ventilation

measurement of gas exchange, dead space, respiratory mechanics 5, 15, 30, 60 minutes from PEEP change (5 and 15 cmH2O)

Study design

Allocation

RANDOMIZED

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

16 Years to 90 Years

Healthy volunteers

Inclusion criteria

* ALI/ARDS patients requiring mechanical ventilation

Exclusion criteria

* Hemodynamic instability * Barotrauma

Design outcomes

Primary

Measure	Time frame
Gas exchange, dead space, respiratory mechanics	5, 15, 30, 60 minutes from PEEP change

Countries

Italy

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026