A Follow-up Colonoscopy Examination in Patients Who Had Previously Undergone Screening Colonoscopy

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00280332

Enrollment

560

Registered

2006-01-23

Start date

2006-03-31

Completion date

2007-11-30

Last updated

2008-05-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colonic Cancer

Keywords

colonic adenoma, colonic advanced neoplasm

Brief summary

* To determine the prevalence of colonic neoplasm in patients who had previously undergone screening colonoscopy * To determine the optimal time interval for re-screening in average risk individuals * To determine potential baseline characteristics that predicts adenoma recurrence

Detailed description

Colorectal cancer (CRC) is the second commonest cancer in Hong Kong, and tends to be increasing. Screening for colorectal cancer can reduce the cancer incidence and mortality by detecting early lesions. However, the best interval for a follow up colonoscopy, particularly for those with normal baseline colonoscopy, remains largely unknown. This study aim to determine the prevalence of colonic neoplasm in average-risk patients who had previously undergone screening colonoscopy and the optimal time interval for re-screening.

Interventions

PROCEDUREcolonoscopy

proform a follow up colonoscopy in the 5 year period from index colonoscopy

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

50 Years to 75 Years

Healthy volunteers

Yes

Inclusion criteria

* Subjects who are previously participated in one of our two screening colonoscopy studies \[Sung, Gastroenterol 2003; Leung, AJG 2004\] * Asymptomatic on first screening colonoscopy * Age\>50and \<75 * No family history of CRC * No other colonoscopy except the baseline screening colonoscopy

Exclusion criteria

* Subjects who refused consent * Subjects who are not warrant follow up colonoscopy

Design outcomes

Primary

Measure	Time frame
The prevalence of advanced colonic adenoma in the re-screening population	5 year from index colonoscopy

Secondary

Measure	Time frame
The time to adenoma adenoma development according to different baseline characteristics of patients and colonoscopy findings	5 years from index colonoscopy

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026