Attention Deficit Hyperactivity Disorder, Conduct Disorder, Oppositional Defiant Disorder, Substance Abuse
Conditions
Keywords
ADHD, Oppositional Defiant Disorder, Conduct Disorder, Substance Use, Drug and Alcohol Use
Brief summary
This study will compare two programs to see if they are helpful in preventing the use of substances in adolescents with attention deficit-hyperactivity disorder (ADHD), oppositional defiant disorder (ODD), or conduct disorder (CD). One of the programs involves working with adolescents and their parent(s) in their home. The other program involves working with adolescents and their parent(s) in an office setting.
Detailed description
In this study phase, 36 patients with a disruptive behavior disorder (DBD - i.e., attention deficit-hyperactivity disorder, oppositional defiant disorder, conduct disorder) and use or abuse of one or more substances will be randomly assigned to treatment using either a standard treatment for DBDs in this age group or the newly developed HBT treatment. Treatment outcomes for the 24 patients assigned to receive HBT will then be compared to outcomes for the 12 patients assigned to receive standard DBD treatment. Specific aims of Phase II include: 1. finalizing the HBT treatment manual and measures of treatment fidelity, therapist competence, and treatment satisfaction; 2. generating estimates of treatment effect sizes for substance use, disruptive behavior, and functional status outcomes, as pilot data for a larger efficacy study, and 3. comparing treatment satisfaction for the two treatment groups. We hypothesize that HBT will lead to significantly lower rates of disruptive behaviors, substance use, and SUDs than with standard treatment, as well as greater concomitant improvements in impairment.
Interventions
BEHAVIORALAdolescent Skills Parent Management Parent-Adol Negotiation
Acute treatment for 12 weeks followed by three monthly booster sessions.
BEHAVIORALTreatment as Usual
Standard outpatient treatment for behavioral problems and substance use
Sponsors
University of Pittsburgh
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
11 Years to 14 Years
Healthy volunteers
No
Inclusion criteria
* Study participants (subjects and parents) must provide written consent and verbal assent * Adolescents aged 11 through 14 of any race or ethnic background, * A DSM-IV disruptive behavior disorder diagnosis (either CD, ODD, ADHD or disruptive behavior disorder not otherwise specified \[DBD NOS\]), * Adolescents who are either using one or more substances regularly (2 or more times a month for 3 consecutive months), and * Acceptable insurance coverage (i.e., participant has insurance that is accepted by the University of Pittsburgh Medical Center \[UPMC\] in the event that they are randomly assigned to the treatment-as-usual \[TAU\] group).
Exclusion criteria
* Full scale IQ below 80; * History of pervasive developmental disorder, schizophrenia or other psychotic disorders, organic mental disorders or eating disorders, * Diagnosis of bipolar disorder, * Recent treatment for substance problems, and/or * Daily use of hard street drugs (i.e., cocaine, methamphetamine, heroin, inhalants).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Rates of substance use and disruptive behaviors | immediately following acute 12 week treatment, at the end of 3 month followup, and at one year follow up |
Countries
United States
Outcome results
None listed