The Aim is to Estimate the Total Amount of Insulin-producing Cells in the Pancreas by MRI.

Pancreatic Beta-Cell Mass And Function Quantification By Means Of Perfusion Imaging

Status

Terminated

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00280085

Enrollment

Registered

2006-01-20

Start date

2005-12-31

Completion date

2007-07-31

Last updated

2009-08-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diabetes Mellitus

Brief summary

Assess pancreatic beta cell function using MR imaging.

Detailed description

The study was terminated on July 31st, 2007. The study was discontinued, as we have not met the primary end point, differentiation between normal volunteers and subjects with type 1 diabetes mellitus. There were no safety concerns.

Interventions

PROCEDUREMR imaging

PROCEDUREGlucose clamp

DRUGArginine

Study design

Allocation

NON_RANDOMIZED

Intervention model

SINGLE_GROUP

Primary purpose

DIAGNOSTIC

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 65 Years

Healthy volunteers

Yes

Inclusion criteria

* Normal Volunteers * T1DM and T2DM subjects

Exclusion criteria

* Concomitant severe conditions

Design outcomes

Primary

Measure	Time frame
Pancreatic perfusion	—

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Apr 2, 2026