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Prevention of Suicide in Primary Care Elderly: Collaborative Trial (PROSPECT)

Prevention of Suicide in Primary Care Elderly: Collaborative Trial

Status
Completed
Phases
Phase 4
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT00279682
Enrollment
1200
Registered
2006-01-19
Start date
1999-05-31
Completion date
2003-08-31
Last updated
2006-01-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Depression, Suicide, Attempted

Keywords

depression, suicide, geriatric, elderly, primary care

Brief summary

The purpose of this study was to determine the effect of a primary care intervention on reducing suicidal ideation and depression in older patients.

Detailed description

Suicide rates are highest in late life; the majority of older adults who die by suicide have seen a primary care physician in preceding months. Depression is the strongest risk factor for late-life suicide and for suicide's precursor, suicidal ideation. The aim of the study was to determine the extent to which an intervention taht combined treatment guidelines with care management reduced rates of depression and suicide ideation in older primary care patients. The study randomized 20 primary care practices from New York City, Philadelphia, and Pittsburgh regions into intervention or usual car. The used a two-stage sampling design that resulted in a representative sample with an oversample of depressed patients (total n=1238 subjects including 598 with a depression diagnosis and 640 with no depression diagnosis). Patients were assessed at baseline, 4, 8, 12, 18 and 24 months.

Interventions

BEHAVIORALtreatment guidelines and depression care management

Sponsors

University of Pennsylvania
CollaboratorOTHER
University of Pittsburgh
CollaboratorOTHER
National Institute of Mental Health (NIMH)
CollaboratorNIH
Forest Laboratories
CollaboratorINDUSTRY
The John A. Hartford Foundation
CollaboratorOTHER
Weill Medical College of Cornell University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
60 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

upcoming appointment with primary care clinician

Exclusion criteria

* inability to give consent * minimental status examination \<18 * ability to communicate in English

Design outcomes

Primary

MeasureTime frame
Hamilton Depression Rating Scale
Scale for Suicide Ideation

Secondary

MeasureTime frame
All cause and cause-specific mortality
disability (Sf12; instrumental activities of daily living)

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 29, 2026