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Benefit of a Collaborative Approach to Improve the Quality of Medicines Use in Elderly Inpatients

Collaborative Approach to Improve the Quality of Medicines Use in Elderly Inpatients - Randomized Controlled Trial

Status
Completed
Phases
Phase 4
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT00279656
Enrollment
180
Registered
2006-01-19
Start date
2003-11-30
Completion date
2005-06-30
Last updated
2006-01-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Frail Elderly Inpatient

Keywords

Frail elderly, Pharmaceutical services, Drug therapy, Geriatrics, Randomized controlled trial, Hospitals, teaching

Brief summary

The purpose of this study is to evaluate the impact of a collaborative approach (geriatric care involving the collaboration with a clinical pharmacist) to optimize the prescription of medicines for elderly inpatients.

Detailed description

Widespread evidence reveals frequent inadequate use of medicines in elderly patients. This includes inappropriate prescribing (overuse, underuse, misuse) that can lead to adverse drug events and drug-related admissions to hospital. In addition, when a patient is transferred from acute care settings to ambulatory care settings, discrepancies in medicines used often occur and can be hazardous. Despite this, only limited data exist on the effectiveness of optimization strategies targeted at frail elderly inpatients. Comparison: elderly inpatients receiving geriatric evaluation and management (GEM) care versus elderly inpatients receiving pharmaceutical care in addition to GEM care.

Interventions

BEHAVIORALPharmaceutical care

Sponsors

Fonds National de la Recherche Scientifique
CollaboratorOTHER
Université Catholique de Louvain
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
ECT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
70 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Patient admitted on the acute geriatric unit of the university teaching hospital Mont-Godinne, Belgium

Exclusion criteria

* a terminal illness and life expectancy of less than 3 month * expected length of stay of 2 days or less * transfer from another unit where the patient had already been cared for by a GEM team * refusal to participate * inclusion during previous admission * no time for the clinical pharmacist to compound the abstracted chart within 3 days of admission

Design outcomes

Primary

MeasureTime frame
Appropriateness of prescribing (using the Medication Appropriateness Index, the Beers criteria, and the ACOVE criteria of underuse) on admission, at discharge, and 3 months post-discharge

Secondary

MeasureTime frame
Polymedication on admission, at discharge, and 1,3,12 months after discharge
Mortality, readmission to hospital and visit to the emergency department 1,3,12 months after discharge
Satisfaction with information received on medicines

Countries

Belgium

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026