Preanalgesic Effect of Gabapentin in Total Knee Repair

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00279487

Enrollment

Registered

2006-01-19

Start date

Unknown

Completion date

2007-08-31

Last updated

2016-10-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain

Keywords

Patients undergoing total knee replacement who received pain management by the following modality:, IV PCA opioid, Local femoral nerve block with 1.5% Mepivacaine & 0.5% Ropivacaine

Brief summary

The purpose of this study is to determine whether gabapentin, as a one time administration prior to a total knee replacement procedure, has opioid sparing effects and a reduction in pain scores.

Interventions

DRUGGabapentin

DRUGPlacebos

Study design

Allocation

NON_RANDOMIZED

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* Patients undergoing total knee replacement who received pain management by the following modality: * Intravenous patient-controlled analgesia (IV-PCA) opioid * Local femoral nerve block with 1.5% mepivacaine 20 ml and 0.5% ropivacaine 20 ml

Exclusion criteria

* Age \< 18 years old

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026