Coronary Artery Disease
Conditions
Keywords
Pain, Depressive Symptoms, Coronary Artery Bypass, Convalescence, Quality of Life, Human Activities
Brief summary
Coronary artery bypass graft (CABG) surgery is performed more frequently on individuals who are older and sicker than in previous years. Increased patient acuity and reduced hospital length of stays leave individuals ill prepared for their recovery following discharge. Individuals experience pain, functional impairment and depressive symptoms following discharge, which persist for 8 weeks in 50% of individuals. Unrelieved pain, functional decline and depressive symptoms predispose individuals to adverse events, impaired health-related quality of life (HRQOL), and increased morbidity and mortality. Existing supports; including printed education materials, community care resources, cardiac rehabilitation programs and nurse-initiated telephone follow-up, fail to address concerns of individuals in this early period following hospital discharge. Despite the positive health outcomes in other patient populations, valid studies examining the impact of telephone-based peer support to men and women after hospital discharge from CABG surgery were not found. It is anticipated that a home-based peer support program, delivered by telephone, will improve recovery and enhance HRQOL for individuals in the early weeks post hospital discharge from CABG surgery.
Detailed description
Coronary artery bypass graft (CABG) surgery is performed more frequently on individuals who are older and sicker than in previous years. This, combined with reduced hospital length of stays, leaves individuals ill prepared for their recovery after discharge. Individuals experience pain, functional impairment and depressive symptoms; which predispose them to adverse events and impaired health-related quality of life (HRQOL). A home-based peer support program may improve recovery outcomes for individuals following CABG surgery. The objectives of this pilot trial were to test the feasibility of all procedures, specifically to determine: 1) an estimate of patient and peer recruitment rates, 2) peer compliance and dose of the intervention, 3) peer satisfaction with orientation, 4) peer support activities offered to patients, and 5) patients' satisfaction with peer support. Additionally, exploratory research questions were used to determine indicators of the effects of peer support on HRQOL, pain, pain-related interference with activities, function, depressive symptoms, and enrolment in cardiac rehabilitation. An 8-week pre-post test RCT design enrolled men and women undergoing CABG surgery at a single site in Southeastern Ontario. Patients were randomized to either a usual care or an intervention group. Patients allocated to usual care received preoperative/postoperative education sessions, a preoperative video/information booklet, and preoperative/postoperative visits from in-hospital peer volunteers. In addition to usual care, patients in the intervention group received individualized education and support via telephone for 8 weeks following hospital discharge from trained peer volunteers. Peer volunteers participated in a 4-hour orientation session. Ninety-three percent of the peers felt adequately prepared for their peer volunteer role and 98% of them initiated calls within 72 hours of the patient's discharge. Peers made an average of 12 calls, less than 30 minutes in duration, to each patient over the 8-week period. Most common support activities provided by the peers included listening to patient concerns, promoting activities, reinforcing rest periods and encouraging achievements. Patients were satisfied with their peer support experience. The intervention group reported improved physical function, role function, less pain and improved cardiac rehabilitation enrolment. The evidence obtained from this pilot trial suggests that a home-based peer support intervention is feasible following CABG surgery. The information will be used to plan a larger multi-centre trial.
Interventions
Sponsors
Study design
Eligibility
Inclusion criteria
(patients): Men and women who * are having first-time non-emergency CABG surgery * are judged ready for discharge * are being discharged to home \[either their own or to family/friends\] * have access to and are able to communicate over a telephone * are able to read, write and understand English Inclusion Criteria (peers): Men and women who * have undergone CABG surgery within the last 5 years * have access to and are able to communicate clearly over a telephone * are able to read, write and understand English * have attended a formal cardiac rehabilitation program * are not associated with the current in-hospital peer volunteer program
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Health-related Quality of Life (SF-36v2-acute Form) | 9 weeks | The SF-36v2 yields a score for each domain of health. All domains are scored on a scale from 0 (negative health) to 100 (positive health), with 100 representing the best possible health state. |
Secondary
| Measure | Time frame |
|---|---|
| Depressive Symptoms (Center for Epidemiologic Studies Depression Scale) | 9 weeks |
| Pain (McGill Pain Questionnaire-Short Form) | 9 weeks |
| Interference With Activities (Brief Pain Inventory-Interference Subscale) | 9 weeks |
| Function (Human Activity Profile) | 9 weeks |
Countries
Canada
Participant flow
Recruitment details
Patients (n=106) were recruited between April-February 2007. Patients having elective coronary artery bypass graft surgery were recruited at the outpatient preadmission class; those having urgent/semi-urgent surgery were recruited in hospital. Peers (n=20) were recruited from the region of Southeastern Ontario during February-March 2006.
Pre-assignment details
One hundred and one patients were randomized at hospital discharge to either usual care or peer support. Five patients who were recruited preoperatively did not meet the eligibility criteria postoperatively for randomization. Of the 20 peers recruited, 6 were unable to participate in one of the training sessions offered in April 2006.
Participants by arm
| Arm | Count |
|---|---|
| Usual Care Patients allocated to usual care received the standard education/support offered to patients post coronary artery bypass graft surgery: preoperative/postoperative group education, preoperative video, general information booklet and preoperative/postoperative visits from in-hospital peer volunteers. | 52 |
| Peer Support In addition to usual care, patients randomly assigned to peer support received individualized pain management and exercise education via home-based peer support delivered by telephone. | 49 |
| Total | 101 |
Withdrawals & dropouts
| Period | Reason | FG000 | FG001 |
|---|---|---|---|
| Overall Study | Lost to Follow-up | 2 | 4 |
Baseline characteristics
| Characteristic | Usual Care | Total | Peer Support |
|---|---|---|---|
| Age Continuous | 64 years STANDARD_DEVIATION 10 | 64 years STANDARD_DEVIATION 10 | 62 years STANDARD_DEVIATION 11 |
| Health-Related Quality of Life (SF-36v2-Acute Form) Bodily Pain | 64.4 units on a scale STANDARD_DEVIATION 29 | 67.1 units on a scale STANDARD_DEVIATION 27.7 | 70.4 units on a scale STANDARD_DEVIATION 25.9 |
| Health-Related Quality of Life (SF-36v2-Acute Form) General Health | 65.3 units on a scale STANDARD_DEVIATION 18.8 | 64.6 units on a scale STANDARD_DEVIATION 19.8 | 64.1 units on a scale STANDARD_DEVIATION 21.5 |
| Health-Related Quality of Life (SF-36v2-Acute Form) Physical Component Score | 41.2 units on a scale STANDARD_DEVIATION 11 | 40.6 units on a scale STANDARD_DEVIATION 11.1 | 40.5 units on a scale STANDARD_DEVIATION 11.3 |
| Health-Related Quality of Life (SF-36v2-Acute Form) Physical Function | 57.0 units on a scale STANDARD_DEVIATION 27.7 | 54.7 units on a scale STANDARD_DEVIATION 29.8 | 54.4 units on a scale STANDARD_DEVIATION 31.7 |
| Health-Related Quality of Life (SF-36v2-Acute Form) Role-Physical | 44.3 units on a scale STANDARD_DEVIATION 32.4 | 40.3 units on a scale STANDARD_DEVIATION 31.6 | 37.6 units on a scale STANDARD_DEVIATION 30.8 |
| Left Ventricular Function Grade 1 (normal) | 32 Participants | 52 Participants | 20 Participants |
| Left Ventricular Function Grade 2 | 15 Participants | 39 Participants | 24 Participants |
| Left Ventricular Function Grade 3 | 4 Participants | 9 Participants | 5 Participants |
| Left Ventricular Function Grade 4 (worst) | 0 Participants | 0 Participants | 0 Participants |
| Left Ventricular Function No Response | 1 Participants | 1 Participants | 0 Participants |
| Marital Status Divorced/Widow/Single | 13 participants | 20 participants | 7 participants |
| Marital Status Married | 38 participants | 80 participants | 42 participants |
| Marital Status No Response | 1 participants | 1 participants | 0 participants |
| Sex: Female, Male Female | 9 Participants | 17 Participants | 8 Participants |
| Sex: Female, Male Male | 43 Participants | 84 Participants | 41 Participants |
Outcome results
Health-related Quality of Life (SF-36v2-acute Form)
The SF-36v2 yields a score for each domain of health. All domains are scored on a scale from 0 (negative health) to 100 (positive health), with 100 representing the best possible health state.
Time frame: 9 weeks
| Arm | Measure | Group | Value (MEAN) | Dispersion |
|---|---|---|---|---|
| Usual Care | Health-related Quality of Life (SF-36v2-acute Form) | Role-Physical | 60.4 units on a scale | Standard Deviation 29.2 |
| Usual Care | Health-related Quality of Life (SF-36v2-acute Form) | General Health | 68.5 units on a scale | Standard Deviation 19.5 |
| Usual Care | Health-related Quality of Life (SF-36v2-acute Form) | Bodily Pain | 72.2 units on a scale | Standard Deviation 25.7 |
| Usual Care | Health-related Quality of Life (SF-36v2-acute Form) | Physical Component Summary Scale | 44.6 units on a scale | Standard Deviation 9.2 |
| Usual Care | Health-related Quality of Life (SF-36v2-acute Form) | Physical Functioning | 72.6 units on a scale | Standard Deviation 22 |
| Peer Support | Health-related Quality of Life (SF-36v2-acute Form) | Physical Component Summary Scale | 47.5 units on a scale | Standard Deviation 8.2 |
| Peer Support | Health-related Quality of Life (SF-36v2-acute Form) | Physical Functioning | 77.0 units on a scale | Standard Deviation 19 |
| Peer Support | Health-related Quality of Life (SF-36v2-acute Form) | Role-Physical | 65.5 units on a scale | Standard Deviation 27.6 |
| Peer Support | Health-related Quality of Life (SF-36v2-acute Form) | Bodily Pain | 78.8 units on a scale | Standard Deviation 21.5 |
| Peer Support | Health-related Quality of Life (SF-36v2-acute Form) | General Health | 72.2 units on a scale | Standard Deviation 17.3 |
Depressive Symptoms (Center for Epidemiologic Studies Depression Scale)
Time frame: 9 weeks
Function (Human Activity Profile)
Time frame: 9 weeks
Interference With Activities (Brief Pain Inventory-Interference Subscale)
Time frame: 9 weeks
Pain (McGill Pain Questionnaire-Short Form)
Time frame: 9 weeks