The Effect of Lifestyle Intervention Versus Gastric Bypass on Various Comorbidities in Morbidly Obese Subjects

Conditions

Diabetes Mellitus, Hypertension, Obstructive Sleep Apnea

Brief summary

This follow up study (\>1 year) aims to compare the effects of lifestyle intervention and gastric by pass surgery on various comorbidities associated with morbid obesity.

Detailed description

Not addressed

Anne-Marie Gabrielsen, Torbjørn Omland, Mette Brokner, Jan Magnus Fredheim, Jens Jordan et al. (9 authors)

BMC Research Notes2016-09-1315 citations

10.1186/s13104-016-2241-x

Reductions in body weight and sleep apnea severity in morbidly obese subjects – Which factors contribute to improvements in lung function and blood gases?

Anne Marie Gabrielsen, Jøran Hjelmesæth, May Brit Lund, Jan Magnus Fredheim, Sverre Lehmann et al. (6 authors)

2015-09-01

10.1183/13993003.congress-2015.pa2408

Gastric bypass surgery has a weight-loss independent effect on post-challenge serum glucose levels.

Hofsø D, Birkeland KI, Holst JJ, Bollerslev J, Sandbu R, Røislien J, Hjelmesæth J.

2015-08-221 citations

10.1186/s13098-015-0066-8

Pulmonary function and blood gases after gastric bypass and lifestyle intervention: a comparative study

Anne-Marie Gabrielsen, May Brit Lund, Johny Kongerud, Karl Erik Viken, Jo Røislien et al. (7 authors)

Clinical Obesity2013-07-089 citations

10.1111/cob.12024

Karlsen TI, Lund RS, Røislien J, Tonstad S, Natvig GK, Sandbu R, Hjelmesæth J.

2013-02-1329 citations

10.1186/1477-7525-11-17

Type 2 diabetes and pre-diabetes are associated with obstructive sleep apnea in extremely obese subjects: a cross-sectional study.

Fredheim JM, Rollheim J, Omland T, Hofsø D, Røislien J, Vegsgaard K, Hjelmesæth J.

2011-09-2547 citations

10.1186/1475-2840-10-84

Beta cell function after weight loss: a clinical trial comparing gastric bypass surgery and intensive lifestyle intervention.

Hofsø D, Jenssen T, Bollerslev J, Ueland T, Godang K, Stumvoll M, Sandbu R, Røislien J, Hjelmesæth J.

2010-11-1549 citations

10.1530/eje-10-0804

Hofsø D, Nordstrand N, Johnson LK, Karlsen TI, Hager H, Jenssen T, Bollerslev J, Godang K, Sandbu R, Røislien J, Hjelmesaeth J.

2010-08-26134 citations

10.1530/eje-10-0514

Interventions

PROCEDUREBariatric surgery

Bariatric surgery as a part of public health service offered treatment seeking morbidly obese patients.

BEHAVIORALIntensive lifestyle intervention

Intensive lifestyle intervention as a part of public health service offered treatment seeking morbidly obese patients.

Study design

Allocation

NON_RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 65 Years

Healthy volunteers

No

Inclusion criteria

* Morbidly obese patients

Exclusion criteria

\-

Design outcomes

Primary

Measure	Time frame	Description
Improvement of co-morbidities	1-year after treatment start	1-year comparative nonrandomized controlled trial

Secondary

Measure	Time frame	Description
Safety issues	1-year	Surgical complications and serious adverse events in both groups as published

Countries

Norway

Outcome results

None listed