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An Intervention to Reduce Inappropriate Prescriptions of Antibiotics for Respiratory Infections in General Practice

Can Antibiotic Prescriptions in Respiratory Tract Infections be Improved? A Cluster Randomized Educational Intervention in General Practice

Status
Completed
Phases
Phase 1Phase 2
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT00272155
Enrollment
118621
Registered
2006-01-04
Start date
2006-01-31
Completion date
2007-03-31
Last updated
2010-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anti-Bacterial Agents, Respiratory Tract Infections

Brief summary

This study will explore the possible effect of a tailored educational intervention towards general practitioners, in order to improve antibiotic prescriptions for respiratory infections.

Interventions

BEHAVIORALEducational intervention

Educational outreach visits to the CME-groups, work-shops, audit and feedback

BEHAVIORALEducational intervention program

The 433 recruited GPs had a total of 1336 717 office consultations of which 171 679 (12.8%) were RTIs encounters for 118 621 different patients. The GPs participated in peer continuing medical education (CME) groups in southern Norway. A multifaceted intervention was tailored, where key components were educational outreach visits to the CME-groups, work-shops, audit and feedback. Prescription Peer Academic Detailers conducted the educational outreach visits. During these visits, evidence-based recommendations of antibiotic prescriptions for RTIs were presented and software handed out for installation in participants PCs, enabling collection of prescription data. These data was linked to corresponding data from the Norwegian Prescription Database (NorPD). Main outcomes are baseline proportion of inappropriate antibiotic prescriptions for RTIs and change in prescription patterns compared to baseline one year after the initiation of the tailored pedagogic intervention.

Sponsors

University of Oslo
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
HEALTH_SERVICES_RESEARCH
Masking
NONE

Eligibility

Sex/Gender
ALL
Healthy volunteers
Yes

Inclusion criteria

* General practitioner * Specialist in general practice

Design outcomes

Primary

MeasureTime frameDescription
Change in antibiotic prescription patterns for respiratory infections1 yearFrom the 1.336.717 office consultations, main outcomes data (baseline proportion of inappropriate antibiotic prescriptions for RTIs and change in prescription patterns compared to baseline) was measured 1 year after the initiation of the tailored pedagogic intervention.

Countries

Norway

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 24, 2026