Adjuvant Radiation in Aortic Valvuloplasty - ARAVA

Status

Terminated

Phases

Phase 3

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00269165

Enrollment

Registered

2005-12-23

Start date

2005-11-30

Completion date

Unknown

Last updated

2010-05-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Aortic Valve Stenosis

Brief summary

This study will examine the effect of external beam radiation therapy in the prevention of restenosis following successful balloon aortic valvuloplasty in severe, symptomatic aortic stenosis.

Interventions

PROCEDUREBalloon Aortic Valvuloplasty

PROCEDUREExternal Beam Radiation

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE

Eligibility

Sex/Gender

ALL

Age

75 Years to No maximum

Healthy volunteers

Inclusion criteria

* Severe Aortic Stenosis * NYHA Class 2-4 CHF Symptoms * Age \> 75 * EuroSCORE \> 7 * Prohibitively High Risk for Aortic Valve Replacement Surgery as Designated by a Cardiac Surgeon

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026