Enhancement of Postocclusive Reactive Hyperaemia by Dipyridamole

Enhancement of Postocclusive Reactive Hyperaemia

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00268554

Enrollment

Registered

2005-12-22

Start date

2005-12-31

Completion date

2006-07-31

Last updated

2008-03-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hyperemia, Hypoxia

Keywords

adenosine, caffeine, dipyridamole

Brief summary

The purpose of this study is to determine whether dipyridamole enhances postocclusive reactive hyperaemia by increasing extracellular adenosine concentrations during ischemia and reperfusion. Furthermore we hypothesize that dipyridamole augments postocclusive reactive hyperaemia by increasing adenosine receptor stimulation.

Interventions

DRUGdipyridamole

DRUGcaffeine

Study design

Allocation

NON_RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

BASIC_SCIENCE

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 50 Years

Healthy volunteers

Yes

Inclusion criteria

* healthy volunteers between 18 and 50 years

Exclusion criteria

* none specified

Design outcomes

Primary

Measure	Time frame
forearm blood flow	—

Countries

Netherlands

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026