Effect of Exercise on Risk-factors of Elderly Women

Effects of Exercise on Multiple Risk Factors and Health Costs in Community Living Elderly Women. The Senior Fitness and Prevention Study (SEFIP)

Status

Terminated

Phases

Phase 3

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00267839

Enrollment

246

Registered

2005-12-21

Start date

2006-01-31

Completion date

2008-03-31

Last updated

2015-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Atrophy

Keywords

exercise, intervention, elderly woman, risk factors, health costs, Osteoporosis, cardiovascular diseases, diabetes, Higher Age

Brief summary

The purpose of this study is to determine whether exercise training may impact relevant risk factors and health costs of community living women older 65 years.

Detailed description

The human aging process is associated with a significant increase of risk factors (i.e. osteoporosis, coronary heard disease, diabetes) and a decline in neuromuscular function impacting independence of the subject. Osteoporosis, diabetes type II and arteriosclerosis are diseases known to correlate with age. Participating in regular sport activities elicits numerous favorable effects that contribute to healthy aging. Unfortunately all existing studies which focus on specific diseases or conditions favour dedicated exercise regimes. However, the complex risk factor scenario of older adults requires multi-purpose exercise programs with impact on all relevant risks. Furthermore so far no exercise study longitudinally determines the effect of an ambulatory exercise program on health cost considering the specific health policy framework of Germany. We hypothesize that regular exercise 1. significantly impact relevant osteoporosis, cardiovascular diseases and diabetes risk factors in elderly subjects 2. significantly reduces health costs in elderly community living women

Interventions

BEHAVIORALphysical exercise, wellness

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

FEMALE

Age

65 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* Community living Caucasian woman ≥ 65 years; live expectation \> 2 years

Exclusion criteria

* secondary osteoporosis * CVD-events including stroke * Participation in other studies * Medication with impact on bone during the last 2 years: * bisphosphonates * parathormone * strontium * HRT, anabolic steroids * calcitonin * natriumflourides * active Vit-D-metabolites * cortisone \> 5 mg/d * medication with impact on falls * low physical performance (\<50 Watt during ergometry) * excessive alcohol-intake

Design outcomes

Primary

Measure	Time frame
health costs after 18 months	baseline 18 month control
falls after 18 months	daily records, analysis after 18 months
Bone parameters after 6, 12 and 18 months	baseline, 6, 12, 18 month-control

Secondary

Measure	Time frame
Functional status after 6, 12, and 18 months	—
CHD- and diabetes-risk-factors (bodyfat, blood lipids, glucose, blood pressure) after 6, 12 and 18 months	—
Quality of live after 12 and 18 months	—

Countries

Germany

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Apr 1, 2026