Anal Cancer, Colon Cancer, Colonic Neoplasms, Rectal Cancer
Conditions
Brief summary
Study the Genetics of Anal Cancer
Detailed description
To determine the status of previously identified anal cancer molecular markers and any correlations with outcome as well as to discover new molecular biomarkers through correlating molecular data with clinical outcome. Study of tissue samples and cells from biopsies of your lesion and blood sample. We hope to learn the role genes and proteins may play in the development of anal cancer. Experiments will be performed using this tissue and blood, include analysis of DNA, analysis of RNA expression levels, analysis of protein levels of important gene products, and development of tissue culture cell lines.
Interventions
OTHERgenetic analysis
standard of care
Sponsors
Stanford University
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
Inclusion Criteria: * Patients with anal tumors * Undergoing surgery for elective colon and rectal surgery
Exclusion criteria
No other patients other than adult patients with anal cancer or high risk for anal cancer refered to Stanford will be enrolled to the study. No Children will be included to the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Genetic analysis of blood sample as well as tissues , will provide us with any possible tumor marker for a better prognostic indicator. | Annual assessment. |
Countries
United States
Outcome results
None listed