Effects of Different Assisted Mechanical Ventilation in Acute Lung Injury (ALI)/Acute Respiratory Distress Syndrome (ARDS) Patients

Effects of Different Assisted Mechanical Ventilation in ALI/ARDS Patients

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00267241

Enrollment

Registered

2005-12-20

Start date

2005-12-31

Completion date

2014-11-30

Last updated

2015-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Respiratory Distress Syndrome, Adult

Keywords

ARDS, ALI, respiratory mechanics, gas exchange, assisted ventilation

Brief summary

The aim of this study is to evaluate the effects in terms of gas exchange, respiratory mechanics and comfort of breathing, of different assisted mechanical ventilation in ALI/ARDS patients.

Detailed description

ALI/ARDS patients (during assisted ventilation) will be ventilated with different types of assisted ventilation (pressure support, pressure support plus sigh, BIPAP, variable ventilation) and gas exchange, comfort of breathing, respiratory mechanics and pattern of breathing will be measured.

Interventions

OTHERMechanical Ventilation

Four different types of assisted ventilation (pressure support, pressure support plus sigh, BIPAP, variable ventilation)

Study design

Allocation

NON_RANDOMIZED

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Patients with ALI/ARDS

Exclusion criteria

* COPD patients * Barotrauma * Hemodynamic instability * Age less than 18

Design outcomes

Primary

Measure	Time frame
Gas exchange and respiratory mechanics	5 minutes

Countries

Italy

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026