Superior Vena Cava Syndrome
Conditions
Brief summary
All patients with symptomatic malignant SVCO deemed suitable for treatment either with radiation therapy or by stenting will be eligible. They will receive whichever treatment is deemed most clinically appropriate. Symptomatic response, time to onset of palliation, duration of symptom control and survival will be assessed.
Interventions
BEHAVIORALManagement and Outcome of SVCO
Sponsors
Princess Margaret Hospital, Canada
University Health Network, Toronto
Study design
Allocation
NON_RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Symptomatic clinical and radiological diagnosis of superior vena caval obstruction. * Underlying histological diagnosis deemed appropriate for palliative radiotherapy as treatment by investigator. Patients with chemosensitive tumours such as small cell lung cancer (both untreated and recurrent), lymphoma and testicular tumours, will be eligible if radiation is deemed to be appropriate treatment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improvement in an index symptom at 4 weeks as recorded by a daily symptom diary | — |
Secondary
| Measure | Time frame |
|---|---|
| Time to onset of palliation | — |
| Duration of symptom control | — |
| Survival | — |
| Number of days spent in hospital | — |
| Requirement for further treatment | — |
Countries
Canada
Outcome results
None listed