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Implementation and Evaluation of Mindfulness-Based Cognitive Therapy in a Health Care Region in Flanders: a Randomized Clinical Trial

Implementation and Evaluation of Mindfulness-Based Cognitive Therapy in a Health Care Region in Flanders: a Randomized Clinical Trial

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT00259506
Enrollment
405
Registered
2005-11-29
Start date
2006-03-31
Completion date
2008-07-31
Last updated
2009-06-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Recurrent Depression

Keywords

Recurrent depression, Mental Health

Brief summary

Research project regarding the possibility to implement and the efficacy of a non-drug, psychotherapeutic intervention (MBCT), in preventing relapse/recurrence of depression.

Detailed description

This trial is based on the following publications: Teasdale JD, Segal ZV, Williams JMG, Ridgeway VA, Soulsby JM, Lau MA. Prevention of relapse / recurrence in major depression by Mindfulness-Based Cognitive Therapy. Journal of Consulting and Clinical Psychology 2000; 68(4): 615-623. Ma SH, Teasdale JD. Mindfulness-Based Cognitive Therapy for depression: replication and exploration of differential relapse prevention effects. Journal of Consulting and Clinical Psychology 2004; 72(1): 31-40.

Interventions

Sponsors

Ministry of the Flemish Community
CollaboratorOTHER_GOV
University Hospital, Ghent
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Age: 18 years and above * place of residence in accordance with a well-defined region (pilot study) * given informed consent * diagnosis of recurrent depression (DSM-IV-TR) * at least 3 depressive episodes in the anamnesis (depression: either primary or secondary diagnosis) * last depressive episode at least 8 weeks ago (DSM-IV-TR) * absence of a present depressive episode * history of treatment by an antidepressant medication * HRSD-score \<14 at baseline assessment (Hamilton Rating Scale for Depression, HRSD-17) * absence of

Design outcomes

Primary

MeasureTime frame
Feasibility to implement MBCT in a Flemish region
Relapse/recurrence of depression after approximately 12 months

Secondary

MeasureTime frame
Coping
Health status
Rumination
Fear
Quality of life

Countries

Belgium

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026