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Effects of Pretreatment With Ibuprofen in Post-Electroconvulsive Therapy (ECT) Headache

Effects of Pretreatment With Ibuprofen in Post- ECT Headache

Status
Withdrawn
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT00258791
Enrollment
0
Registered
2005-11-28
Start date
2012-01-31
Completion date
2012-05-31
Last updated
2012-09-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mental Disorders

Keywords

Psychiatric disorders, ECT, Headache, Ibuprofen

Brief summary

The purpose of the study is to determine whether ibuprofen reduces post-ECT headache or reduces its severity.

Detailed description

The aim of the study is to compare the severity of headache between patients who are receiving ibuprofen prior to ECT treatment with patients receiving placebo prior to ECT treatment. Patients will be randomly assigned to receive either 600 mg ibuprofen 90 min prior to treatment or placebo orally, blinded to patient, physician and treatment team. Patients will be asked about their headache with a visual analogue scale (VAS) 2 hours prior to and within 2 hours after treatment, 2-month, 6- month and 1 year follow-up \[5\].

Interventions

DRUGIbuprofen

Sponsors

Norwegian University of Science and Technology
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Patients receiving ECT

Exclusion criteria

* Pregnancy, contraindications to ibuprofen

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026