Optimal Pharmacological Therapy In Implantable Defibrillator Patients (OPTIC)

Status

Completed

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00257959

Enrollment

400

Registered

2005-11-24

Start date

2001-01-31

Completion date

2004-10-31

Last updated

2006-07-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ventricular Tachycardia

Brief summary

This is an open parallel design randomized trial of amiodarone plus a beta blocker vs a beta blocker alone vs sotalol for the prevention of ICD shocks in patients receiving an ICD for spontaneous or inducible ventricular tachycardia or fibrillation

Interventions

DRUGamiodarone beta blocker sotalol

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

spontaneous or inducible ventricular tachycardia or fibrillation -

Exclusion criteria

Design outcomes

Primary

Measure	Time frame
ICD shock for any cause	—

Countries

Canada

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Apr 12, 2026