Aortic Valve Disease, Coronary Artery Disease
Conditions
Brief summary
Controversies still exists concerning the overall clinical effects of blood-based vs. crystalloid- based cardioplegic solution for myocardial protection during cardiac arrest. Both techniques are used world-wide. No larger prospectively randomized studies comparing the two methods have been reported. The aim of this study is to collect a large number of clinical data to create a proper basis for evaluation of the two techniques.
Detailed description
All patients admitted for aortic valve replacement with or without concomitant CABG and operated by E.Ø. or G.T. are included in the study. All preoperative, operative and postoperative data are prospectively recorded, focusing on clinical outcome parameters
Interventions
PROCEDUREMyocardial protection techniques
Sponsors
Oslo University Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
Aortic valve replacement
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Myocardial function, | — |
| postoperative ventilatory support, postoperative arrhythmia, | — |
| blood transfusions, | — |
| physical recovery, | — |
| mortality. | — |
Secondary
| Measure | Time frame |
|---|---|
| Costs | — |
Countries
Norway
Outcome results
None listed