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Isolated Mild Fetal Ventriculomegaly and Neurodevelopmental Outcome

Isolated Mild Fetal Ventriculomegaly and Neurodevelopmental Outcome

Status
Terminated
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT00256906
Enrollment
20
Registered
2005-11-22
Start date
2006-01-31
Completion date
2012-01-31
Last updated
2018-03-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fetal Development

Keywords

lateral ventricles, fetal ventriculomegaly

Brief summary

Isolated mild fetal ventriculomegaly is a common finding in fetal ultrasound examinations. When the ventricular diameter is more than 15 mm it is usually considered as severe and connected to other malformations. Most of these children will be severely affected later in life. Less than 10 mm ventricular width considered as normal. The current medical knowledge can not answer questions regarding future development of children who were diagnosed to suffer from mild (10-14.9 mm) brain ventriculomegaly during the pregnancy. We would like to assess the development and neurological status of all children who were diagnosed as mild ventriculomegaly during the pregnancy in the last 6 years and to prospectively follow up all the children who will be diagnosed from the beginning of the study on for 6 years. We hypothesized that the course of their development is different than of other children.

Detailed description

Study design: Patients: 1. All children who are currently 5-6 year-old who suffered from isolated fetal mild brain ventriculomegaly during the pregnancy. 2. All children who will be diagnosed with isolated fetal mild brain ventriculomegaly during the pregnancy from the beginning of the study for 6 years. Methods: 1. All children will be examined by a pediatric neurologist who will perform a neuro-developmental assessment appropriate for age. The neurologist will decide individually whether there is a need for more medical tests. 2. All children will be assessed by a psychologist who will perform WIPPSI or BAYLEY tests according to age.

Interventions

None listed

Sponsors

Hadassah Medical Organization
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
1 Years to 10 Years
Healthy volunteers
No

Inclusion criteria

* All children who were or are diagnosed with isolated fetal mild ventriculomegaly

Exclusion criteria

* Anatomic malformations * IVH * Hydrocephalus * Metabolic disorder * CNS infection

Countries

Israel

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026