Borderline Personality Disorder
Conditions
Keywords
Borderline Personality Disorder, BPD, Dialectical Behavior Therapy, DBT, Escitalopram, Lexapro
Brief summary
Subjects will receive six months of DBT, consisting of one 90-minute group and one 60-minute individual session per week as well as telephone availability of the individual therapist. Half the subjects will concurrently receive escitalopram while half will receive placebo, in a randomized double-blind design.
Interventions
BEHAVIORALDialectical Behavioral Therapy
DRUGEscitalopram
Sponsors
Bronx VA Medical Center
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE
Eligibility
Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
No
Inclusion criteria
Is a male or female between 18 and 60 who meets criteria for Borderline Personality Disorder and has been off psychotropic medications for at least 2 weeks (6 weeks for fluoxetine). \-
Exclusion criteria
Meets criteria for Schizophrenia, Bipolar Disorder, Mental Retardation, current or recent Substance Dependence or a current Major Depressive Episode. Subjects also should not currently be in individual psychotherapy. (Case management and work therapy programs are allowed.) \-
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Measures of impulsivity, aggression, affective impulsivity, immediate and delayed memory, and cognitive processing at baseline, 6 months and 9 months | — |
Countries
United States
Contacts
Primary ContactEmily Hart
Outcome results
None listed