Skip to content

Morphofunctional Imaging and Developmental Dyslexia

Morphofunctional Imaging and Developmental Dyslexia

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT00254644
Acronym
PHR04-CH/DYS
Enrollment
32
Registered
2005-11-16
Start date
2007-02-28
Completion date
2008-02-29
Last updated
2017-01-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Developmental Dyslexia

Keywords

phonological treatment, language, fMRI

Brief summary

Developmental dyslexia is a frequent learning disability. The aim of this study is to analyze cortical thickness and phonological treatment in right handed adults with developmental dyslexia. They are compared to control adults paired with age and laterality. To study phonological treatment, the researchers used functional magnetic resonance imaging (fMRI) with a rime judgement task and silent word generation.

Interventions

PROCEDUREMorphological and functional MRI

one time

Sponsors

University Hospital, Tours
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
MALE
Age
18 Years to 35 Years
Healthy volunteers
Yes

Inclusion criteria

* Developmental dyslexia according to Critchley. * Normal performance intelligence quotient (PIQ) * Age: 18-35 years * Sex: Male * Right handed * No hearing deficit.

Exclusion criteria

* No head injury * No attention deficit hyperactivity disorder (ADHD)

Design outcomes

Primary

MeasureTime frameDescription
Cortical thickness2 yearsThe average cortical thickness maps of healthy subjects and dyslexic will be compared hemisphere by hemisphere. This will identify whether there are cortical areas including cortical thickness differed significantly between normal and dyslexic.ts of different ages

Secondary

MeasureTime frameDescription
Average cortical thickness2 yearsFor each group, cortical thickness maps of average left and right hemispheres are compared. This will identify whether there is an asymmetry left / right in terms of cortical thickness in normal subjects and dyslexic.

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026