End Stage Liver Disease, End Stage Renal Disease, Substance-Related Disorders
Conditions
Keywords
End stage liver disease, End stage renal disease, Substance-Related Disorders
Brief summary
The purpose of this study is to test a novel distance-based (telephone) intervention to help transplant candidates with current or recent substance abuse to stay clean and sober both prior and following transplant surgery.
Detailed description
Participants who need a liver or renal transplant and who are ineligible due to current or recent (past 6 months) alcohol and/or other drug abuse are being recruited from the transplant programs at St. Luke's-Roosevelt Hospital Center (renal), Columbia Presbyterian Hospital (renal/liver) and Virginia Commonwealth University Medical Center (liver). Baseline and follow-up computer-assisted assessments and structured clinical interviews along with collection of biological samples (urine, hair) will occur in the transplant clinics; however, phone counseling sessions originate at St. Luke's. Participants are randomly assigned to one of two treatments: (1) usual care (no phone counseling) or (2) usual care + counseling. The telephone counseling sessions are designed to help participants become motivated to remain abstinent and improve other health behaviors such as sleep or stress management.
Interventions
BEHAVIORALTAP
12-session motivational interviewing-based telephone intervention.
OTHERTAU
The usual care group will receive the same medical services they would otherwise receive if they were not in this study.
Sponsors
St. Luke's-Roosevelt Hospital Center
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* End stage liver or renal disease * Having used drugs or alcohol during the past 6 months * Turned down for transplant due to current or recent substance use * Access to telephone
Exclusion criteria
* Psychotic or other unstable serious psychiatric disorders that preclude full, active participation * Moderate to severe hepatic encephalopathy * Non-English speaking
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Abstinence | 3 month time frame |
Secondary
| Measure | Time frame |
|---|---|
| Stage of Change, illness response, psychological stress | 3 month time frame |
Countries
United States
Outcome results
None listed