Cocaine Dependence
Conditions
Keywords
Substance Abuse, Contingency Management
Brief summary
The purpose of this study is to compare voucher-based contingency management (CM) procedures to a lower-cost CM system that provides opportunities to win prizes. Cocaine-dependent outpatients are randomly assigned to (a) standard treatment, (b) standard treatment plus usual magnitude prize CM, (c) standard treatment plus higher magnitude prize CM, or (d) standard treatment plus voucher CM. Urine and breath samples are collected 2-3x/week for 14 weeks. Follow-up interviews are conducted at 1,3,6 and 9 months following intake during which substance use and psychosocial functioning are assessed.
Interventions
BEHAVIORALContingency management
Rewards (prizes) for abstinence
Sponsors
National Institute on Drug Abuse (NIDA)
UConn Health
Study design
Allocation
RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* age \> 18 years * current DSM-IV diagnosis of cocaine dependence * received methadone treatment at the clinic for at least 3 months * on a stable dose of methadone (no changes in dosing) for at least one month and not presently requesting a dose alteration * submitted one or more clinic-collected cocaine positive urine samples in the previous 3 months * English speaking * pass a brief quiz related to understanding of the informed consent form
Exclusion criteria
* have a serious, uncontrolled psychiatric illness (e.g., acute schizophrenia, bipolar disorder, severe or psychotic major depression, or suicide risk) * have dementia (\<23 on the Mini Mental State Exam; Folstein et al. 1975) * are in recovery from pathological gambling
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cocaine use | baseline and each follow-up |
Countries
United States
Outcome results
None listed