Hypertension
Conditions
Keywords
hypertension, ambulatory BP, office resting BP, hydrochlorothiazide, stress reduction, self-help, psychotherapy, efficacy
Brief summary
The objective of the study is to determine whether psychological therapy (self-help or individualized intense stress management) is different than a single drug treatment in terms of their effectiveness for lowering blood pressure.
Interventions
DRUGHydrochlorothiazide
Not recorded in detailed description.
Sponsors
Canadian Institutes of Health Research (CIHR)
University of British Columbia
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
19 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* must be at least 19 years of age * subjects can be male or female * subjects must have an average resting blood pressure of \>140 systolic pressure an/ or \>90 diastolic pressure off anti-hypertensive medication
Exclusion criteria
* must not be on more than 2 blood pressure lowering drugs * must not have known or suspected of having secondary hypertension on initial examination * must not be pregnant or anticipating pregnancy during study period * must not have history of allergy, hypersensitivity or intolerance to diuretics * must not have medical condition that may result in an unacceptable risk of complications due to uncontrolled hypertension during time period of study * must not have average resting BP readings that exceed 190 systolic, or 115 diastolic, or have two consecutive readings of 180 systolic or 110 diastolic
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Day time ambulatory BP | See description |
Secondary
| Measure | Time frame |
|---|---|
| 24 hour ambulatory BP, and office resting BP | See description |
Countries
Canada
Outcome results
None listed