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Optimizing Antibiotic Use in Long Term Care

Optimizing Antibiotic Use in Long Term Care

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT00243360
Enrollment
Unknown
Registered
2005-10-24
Start date
2001-01-31
Completion date
2003-07-31
Last updated
2005-10-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Urinary Tract Infection, Antibiotic Use

Keywords

Urinary tract infections,, antibiotic use,, long term care facilities

Brief summary

The purpose of this study was to determine if a multi-faceted intervention to implement diagnostic and therapeutic algorithms for management of suspected urinary infection in nursing home residents could reduce antibiotic prescribing for urinary indications in this population.

Detailed description

Antibiotic use is intense in nursing homes and frequently inappropriate when prescribed for urinary indications. Evidence from randomized controlled trials suggests that treatment of asymptomatic bacteriuria, the presence of bacteria in the urine in the absence of urinary symptoms, is not beneficial. Despite this, one in three prescriptions for urinary indications are for asymptomatic bacteriuria. To improve antibiotic prescribing in this setting we conducted a cluster randomized trial of a strategy to implement diagnostic and treatment algorithms for urinary infection. 24 nursing homes were randomized to either the intervention (implemented at the nursing home level using a multi-faceted approach: small group interactive sessions for nurses, one-on-one interviews for physicians, videotapes, written material, and outreach visits) or to usual care.

Interventions

BEHAVIORALdiagnostic and treatment clinical algorithms

Sponsors

Agency for Healthcare Research and Quality (AHRQ)
Lead SponsorFED

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
ECT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
0 Years to No maximum
Healthy volunteers
No

Inclusion criteria

1. Individuals- all residents eligible 2. Nursing homes * Free standing long term care facilities with \>100 beds * No stated policy for diagnosis or treatment of urinary tract infections * The facility agrees to refrain from introducing new strategies for antibiotic utilization or clinical pathways during study

Exclusion criteria

\-

Design outcomes

Primary

MeasureTime frame
Antimicrobial prescriptions

Secondary

MeasureTime frame
Urinary cultures,
hospitalizations, deaths

Countries

Canada

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026